A new report from the National Institutes of Health provides a road map on how to improve the nation’s oral health. Released by NIH’s National Institute of Dental and Craniofacial Research (NIDCR), the report emphasizes the importance of oral health, and challenges to the creation of more equitable access to oral health services. Potential roles for health philanthropy are highlighted including grantmaking and policy engagement regarding insurance access, community health education, and school-based dental services.