Foundations play a vital role in the nonprofit sector, funding everything from safety net services to social innovation. Like many businesses, philanthropic organizations altered their ways of doing business in response to the COVID-19 pandemic. The health sector, including hospitals and other health care settings along with public health organizations, were deeply affected by the magnitude of illness and the polarization of the pandemic response. To understand exactly how the business of health grantmaking shifted during COVID-19, Jennifer Chubinski and Allen Smart conducted in-depth interviews with health foundation leaders from around the country to learn what changed in their grantmaking strategies and practices.